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Renewed hope for gene therapy in rare disease
Renewed hope for gene therapy in rare disease
Between 30 and 40 million people in Europe suffer from rare diseases —many of them children. As most of these diseases have genetic origins, gene therapy is a major hope for their future cure .
Secrets of youth, based on prevention
Secrets of youth, based on prevention
We age in two ways. There is the ageing we count by clock and calendar. And then there is biological ageing. The latter is written into our genes. But, it is also influenced by our lifestyle and history.
Ana Valdes – Twins studies to identify the molecular cause of ageing
Ana Valdes – Twins studies to identify the molecular cause of ageing
What makes us age biologically? We have always been intrigued by this question. Yet, it remains a fundamental research challenge.  Now, the EU-funded project, EurHEALTHAgeing , aims to draw together studies of early development with those on longevity and ageing.
Picking the right virus candidate for gene therapy
Picking the right virus candidate for gene therapy
Viruses often get bad press. Likened to Trojan horses they are often associated with disease. But, i t is precisely because of their infectious nature that they can potentially be used as gene vectors - which are vehicles loaded with good copies of malfunctioning genes - and delivered to cells.
Healing bone defects using regenerative medicine
Healing bone defects using regenerative medicine
Bone is one of the most frequently transplanted tissues. And the demand is rising. Transplants treat large defects like those caused by trauma, complicated fractures, tumour resection or osteoporosis. ...
Fighting resistance to antimalarial drug
Fighting resistance to antimalarial drug
When it comes to the emergence of antimalarial drug resistance, it’s not a question of ‘if’ but ‘when’.
Back Pain: New Tools for Prevention
Back Pain: New Tools for Prevention
European researchers and clinicians are working hand in hand to unveil the mechanisms leading to back pain, likely the most widespread chronic pathology among humans .
Physical work, not the main cause of intervertebral disc degeneration
Physical work, not the main cause of intervertebral disc degeneration
Even if you do not suffer from pain in the intervertebral discs in your lower back, it is a sure bet that you know someone who does. Yet, surprisingly little is known about what causes this disc degeneration .
Jill Urban – Genetic factors play a role in lower back pain
Jill Urban – Genetic factors play a role in lower back pain
Lower back pain is a broad yet subtle subject. It has widely been associated with early degeneration of the discs of the human spine.
Mapping proteins in space and time within cells
Mapping proteins in space and time within cells
The human genome and those of several other organisms have been mapped. But it is proteins that perform the majority of biological functions within every organism .
Peering down protein-DNA interactions to better understand how genes work
Peering down protein-DNA interactions to better understand how genes work
Almost every one of our cells has an entire copy of our genome. But only differing subsets of genes are active and expressed in any given cell. Epigenetics is the study of how the activity of our genes is controlled and regulated .
The art of enrolling preterm babies in clinical trials
The art of enrolling preterm babies in clinical trials
Around the world more and more babies are born preterm, according to a WHO report from 2012. Despite medical advances, very small preterm infants may suffer from various complications and diseases, or even die .
Parasite surveillance to support policy against drug resistance
Parasite surveillance to support policy against drug resistance
Leishmaniasis is a tropical disease known in Europe because it affects dogs. It is caused by the Leishmania parasite carried by sandflies . However, several types of the parasite also affect humans in several regions in the world.
Mum’s diet mirrors child’s food allergies
Mum’s diet mirrors child’s food allergies
About 20 million Europeans are subject to food allergies. Now scientists are looking at these allergies in new ways. It involves the food industry in its work and pays special attention to the link between early diets and allergy in later life .
New therapy against rare gene defects
New therapy against rare gene defects
European scientists set up new therapeutic approaches to tackle specific Lysosomal Storage Disorders: a new drug combination and enzyme replacement therapy against Pompe disease and gene therapy against MPS V I (Mucopolysaccharidosis VI).
Brain model pins down motor decisions
Brain model pins down motor decisions
Talking or reading. Texting a message or listening. The dilemma of choosing between various tasks is not an invention of the modern information age. Humans and all vertebrates have to prioritise their actions.
Towards effective spatial mosquito repellent
Towards effective spatial mosquito repellent
Global warming is leading to an increase in mosquito-borne diseases such as malaria . It is considered the plague of developing countries. According to the World Health Organisation , it is responsible for one child death every minute.
Better diagnostics for thrombosis are a matter of resources
Better diagnostics for thrombosis are a matter of resources
Cost-effectiveness is paramount for any new medical technology. If pharmaceutical companies do not see a profit, new drugs will never see the light of day.
When air quality governs traffic management
When air quality governs traffic management
Poor air quality costs Europe more than €700 million per year, in health expenditures and loss of economic performance, according to official EU sources.
When your water is contaminated
When your water is contaminated
Statistically, drinking water in Europe is the safest in the world. But according to the World Health Organisation every year more than 300.000 Europeans are falling ill due to contaminated tab water. ...
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