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Picking the right virus candidate for gene therapy
Picking the right virus candidate for gene therapy
Viruses often get bad press. Likened to Trojan horses they are often associated with disease. But, i t is precisely because of their infectious nature that they can potentially be used as gene vectors - which are vehicles loaded with good copies of malfunctioning genes - and delivered to cells.
Healing bone defects using regenerative medicine
Healing bone defects using regenerative medicine
Bone is one of the most frequently transplanted tissues. And the demand is rising. Transplants treat large defects like those caused by trauma, complicated fractures, tumour resection or osteoporosis. ...
Fighting resistance to antimalarial drug
Fighting resistance to antimalarial drug
When it comes to the emergence of antimalarial drug resistance, it’s not a question of ‘if’ but ‘when’.
Back Pain: New Tools for Prevention
Back Pain: New Tools for Prevention
European researchers and clinicians are working hand in hand to unveil the mechanisms leading to back pain, likely the most widespread chronic pathology among humans .
Physical work, not the main cause of intervertebral disc degeneration
Physical work, not the main cause of intervertebral disc degeneration
Even if you do not suffer from pain in the intervertebral discs in your lower back, it is a sure bet that you know someone who does. Yet, surprisingly little is known about what causes this disc degeneration .
Jill Urban – Genetic factors play a role in lower back pain
Jill Urban – Genetic factors play a role in lower back pain
Lower back pain is a broad yet subtle subject. It has widely been associated with early degeneration of the discs of the human spine.
Mapping proteins in space and time within cells
Mapping proteins in space and time within cells
The human genome and those of several other organisms have been mapped. But it is proteins that perform the majority of biological functions within every organism .
Peering down protein-DNA interactions to better understand how genes work
Peering down protein-DNA interactions to better understand how genes work
Almost every one of our cells has an entire copy of our genome. But only differing subsets of genes are active and expressed in any given cell. Epigenetics is the study of how the activity of our genes is controlled and regulated .
Parasite surveillance to support policy against drug resistance
Parasite surveillance to support policy against drug resistance
Leishmaniasis is a tropical disease known in Europe because it affects dogs. It is caused by the Leishmania parasite carried by sandflies . However, several types of the parasite also affect humans in several regions in the world.
Mum’s diet mirrors child’s food allergies
Mum’s diet mirrors child’s food allergies
About 20 million Europeans are subject to food allergies. Now scientists are looking at these allergies in new ways. It involves the food industry in its work and pays special attention to the link between early diets and allergy in later life .
New therapy against rare gene defects
New therapy against rare gene defects
European scientists set up new therapeutic approaches to tackle specific Lysosomal Storage Disorders: a new drug combination and enzyme replacement therapy against Pompe disease and gene therapy against MPS V I (Mucopolysaccharidosis VI).
Brain model pins down motor decisions
Brain model pins down motor decisions
Talking or reading. Texting a message or listening. The dilemma of choosing between various tasks is not an invention of the modern information age. Humans and all vertebrates have to prioritise their actions.
Towards effective spatial mosquito repellent
Towards effective spatial mosquito repellent
Global warming is leading to an increase in mosquito-borne diseases such as malaria . It is considered the plague of developing countries. According to the World Health Organisation , it is responsible for one child death every minute.
Better diagnostics for thrombosis are a matter of resources
Better diagnostics for thrombosis are a matter of resources
Cost-effectiveness is paramount for any new medical technology. If pharmaceutical companies do not see a profit, new drugs will never see the light of day.
Maria Leon Roux – a taxation approach to deter smokers
Maria Leon Roux – a taxation approach to deter smokers
The International Agency for Research on Cancer ( IARC ) has produced a handbook detailing the scientific evidence on tobacco pricing and tobacco control entitled: Effectiveness of Tax and Price Policies for Tobacco Control .
To save lives, raise tobacco taxes
To save lives, raise tobacco taxes
Smoking is the largest single cause of preventable premature death and disease , accounting for some 650,000 premature deaths each year in the European Union, according to official EU statistics.
Advances in Treating Huntington’s Disease
Advances in Treating Huntington’s Disease
Juliet Ross is suffering from Huntington’s Disease, a rare neurological disorder that affects one in 10.000 people. Due to a genetic defect, her body produces a toxic protein that damages neurons in her brain .
New Blood Test for Schizophrenia
New Blood Test for Schizophrenia
This test evaluates the presence of certain proteins in blood samples of patients. Sabine Bahn from the University of Cambridge says that the new test is able to diagnose schizophrenia with a certainty of 83% and depression with a certainty of about 90% .
Sabine Bahn: biomarkers to diagnose severe psychotic disorders
Sabine Bahn: biomarkers to diagnose severe psychotic disorders
Sabine Bahn is a neurobiologist, psychiatrist and director of the Cambridge Centre for Neuropsychiatric Research at the University of Cambridge, UK.
Schizophrenia enters the molecular diagnostics era
Schizophrenia enters the molecular diagnostics era
With a drop of blood and some laboratory analyses, doctors have been able to tell patients whether they suffer from diabetes or some sort of cancer.
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